Laparoscopic liver resection for colorectal cancer liver metastases: long-term five- and ten-year survival

Presenter: Epameinondas Dogeas MD | University of Pittsburgh Medical Center Background: Laparoscopic liver resection (LLR) for colorectal cancer metastases (CRLM) is well-established with clinical short-term benefits, however data lacking on long-term (10 year) oncologic outcomes. Methods: A retrospective review a prospectively maintained database at single Western center was performed to identify patients who underwent LLR CRLM between 2002-2017. Kaplan-Meier analysis used estimate their Recurrence Free Survival (RFS) and Overall (OS). Results: 140 were identified that had undergone LLR. Median age surgery 64 years. The mean number lesions 1.4 the average size largest tumor 2.6 cm. Disease distribution unilobar in 88% patients. Liver pure laparoscopic fashion 44%, hand-assisted 44% robot-assisted 10% cases. Major hepatectomy 15% Simultaneous ablation 11% R0 margin achieved 87% length post-operative hospital stay 4.5 days. follow-up 48 months. In terms actual OS, 61% alive 5 years 38% 10 At time last follow-up, 50% evidence disease recurrence 39% 5-year 37% 10-year RFS. Conclusion: These findings indicate minimally-invasive as part treatment strategy CLRM can lead excellent outcomes, more than third our cohort cancer-free Although majority recurrences observed within five after LLR, some did recur 10, therefore should be followed least post-operatively. However, no or deaths reached mark could reasonably considered cured from an standpoint.